Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor
نویسندگان
چکیده
منابع مشابه
Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor.
BACKGROUND The organophosphate insecticide chlorpyrifos (CPF), widely used for agricultural purposes, has been linked to neurodevelopmental deficits. Possible motor effects at low to moderate levels of exposure have not been evaluated. METHODS Prenatal exposure to CPF was measured in umbilical cord blood in a sample of 263 inner-city minority children, who were followed prospectively. At appr...
متن کاملSublethal exposure of organophosphate pesticide chlorpyrifos alters cellular iron metabolism in hepatocytes and macrophages.
Chlorpyrifos (CPF) is commonly used for agricultural and domestic applications, and its contamination is widely detected in environmental media, and in a broad spectrum of field crops, fruits and vegetables. CPF exposure causes many adverse effects on human health including hepatoxicity, neurotoxicity and endocrine disruption. However, few studies have been conducted thus far to investigate the...
متن کاملSeven-Year Neurodevelopmental Scores and Prenatal Exposure to Chlorpyrifos, a Common Agricultural Pesticide
BACKGROUND In a longitudinal birth cohort study of inner-city mothers and children (Columbia Center for Children's Environmental Health), we have previously reported that prenatal exposure to chlorpyrifos (CPF) was associated with neurodevelopmental problems at 3 years of age. OBJECTIVE The goal of the study was to estimate the relationship between prenatal CPF exposure and neurodevelopment a...
متن کاملAssociations of Prenatal Exposure to Organophosphate Pesticide Metabolites with Gestational Age and Birth Weight
BACKGROUND Prenatal exposure to organophosphate (OP) insecticides, a widely used class of pesticides, may be associated with decreased gestational age and lower birth weight. Single nucleotide polymorphisms in paroxanase (PON1) enzyme genotypes may modify the relationships between OP exposure and perinatal outcomes. OBJECTIVE We examined the relationship of prenatal OP insecticide exposure, m...
متن کاملBiological monitoring of genotoxicity to organophosphate pesticide exposure among rice farmers: Exposure-effect continuum study
Background: This study has used biomarker of exposure-effect continuum to examine the biological characteristics of organophosphate (OP) toxicity and its genotoxic effect among rice farmers. Materials and Methods: A cross-sectional study was conducted among 160 pesticide exposed rice farmers and 160 adults from the fishing village as the unexposed group. They share the common socio-economical ...
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ژورنال
عنوان ژورنال: NeuroToxicology
سال: 2015
ISSN: 0161-813X
DOI: 10.1016/j.neuro.2015.09.004